Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.35 |
| ▸ | GSK3B | P49841 | 3/20 | 0.35 |
| ▸ | CSNK1G2 | P78368 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29986708 | 0.92 | FGFR1 (0.37) | GRM5CSF1RPIK3CGCSNK1A1CSNK1D | |
| SCHEMBL24667651 | 0.92 | FGFR1 (0.37) | GRM5CSF1RPIK3CGCSNK1A1CSNK1D | |
| SCHEMBL29165253 | 0.91 | GRM5 (0.36) | GRM5CSF1RPIK3CGCSNK1A1CSNK1D | |
| SCHEMBL24667720 | 0.91 | GRM5 (0.36) | GRM5CSF1RPIK3CGCSNK1A1CSNK1D | |
| SCHEMBL29987560 | 0.91 | GRM5 (0.36) | GRM5CSF1RPIK3CGCSNK1A1CSNK1D | |
| SCHEMBL24667358 | 0.90 | GRM5 (0.36) | GRM5CSF1RPIK3CGCSNK1A1CSNK1D | |
| SCHEMBL24667405 | 0.90 | GRM5 (0.38) | GRM5CSF1RPIK3CGCSNK1A1CSNK1D | |
| SCHEMBL29987217 | 0.90 | GRM5 (0.36) | GRM5CSF1RPIK3CGCSNK1A1CSNK1D | |
| SCHEMBL24667401 | 0.90 | GRM5 (0.36) | GRM5CSF1RPIK3CGCSNK1A1CSNK1D | |
| SCHEMBL29987383 | 0.90 | GRM5 (0.36) | GRM5CSF1RPIK3CGCSNK1A1CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117412960-A | Isoindolinone compounds and imaging agents for imaging huntingtin | CHDI基金会股份有限公司 | 2024-01-16 | — | — | CN | disclosed |