Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.71 |
| ▸ | DDB1 | Q16531 | 15/20 | 0.71 |
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
| ▸ | IKZF3 | Q9UKT9 | 4/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.54 |
| ▸ | IL1B | P01584 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.54 |
| ▸ | CCNK | O75909 | 1/20 | 0.52 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30772319 | 1.00 | CRBN (0.71) | CRBNDDB1STAT3IKZF3TNF | |
| SCHEMBL30772326 | 1.00 | CRBN (0.71) | CRBNDDB1STAT3IKZF3TNF | |
| SCHEMBL21996714 | 0.97 | DDB1 (0.67) | CRBNDDB1STAT3IKZF3TNF | |
| SCHEMBL30001287 | 0.86 | CRBN (0.92) | CRBNDDB1STAT3IKZF3TNF | |
| SCHEMBL29262135 | 0.86 | CRBN (0.92) | CRBNDDB1STAT3IKZF3TNF | |
| SCHEMBL21996948 | 0.86 | DDB1 (0.55) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL27313806 | 0.86 | DDB1 (0.70) | CRBNDDB1STAT3IKZF3TNF | |
| SCHEMBL25358828 | 0.85 | CRBN (0.77) | CRBNDDB1STAT3IKZF3TNF | |
| SCHEMBL25224286 | 0.85 | CRBN (0.77) | CRBNDDB1STAT3IKZF3TNF | |
| SCHEMBL25219673 | 0.85 | CRBN (0.77) | CRBNDDB1STAT3IKZF3TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510504-A | Protein kinase degradation agent, medicine and application | 深圳市新樾生物科技有限公司 | 2024-02-06 | — | — | CN | disclosed |