Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1787716 | 0.84 | PTGDR2 (0.64) | PTGDR2AKR1B1CYP2C9PTGDR | |
| SCHEMBL2088388 | 0.79 | PTGDR2 (0.52) | PTGDR2AKR1B1CYP2C9PTGDR | |
| SCHEMBL5749192 | 0.79 | PTGDR2 (0.60) | PTGDR2AKR1B1CYP2C9PTGDR | |
| SCHEMBL1788163 | 0.73 | PTGDR2 (0.66) | PTGDR2AKR1B1CYP2C9PTGDR | |
| SCHEMBL1785965 | 0.73 | PTGDR2 (0.56) | PTGDR2AKR1B1CYP2C9PTGDR | |
| SCHEMBL1785003 | 0.73 | PTGDR2 (0.56) | PTGDR2AKR1B1CYP2C9PTGDR | |
| SCHEMBL5739375 | 0.72 | PTGDR2 (0.55) | PTGDR2AKR1B1CYP2C9PTGDR | |
| SCHEMBL1467977 | 0.72 | PTGDR2 (0.62) | PTGDR2AKR1B1CYP2C9PTGDR | |
| SCHEMBL1786162 | 0.71 | PTGDR2 (0.62) | PTGDR2CYP2C9PTGDR | |
| SCHEMBL3006606 | 0.68 | PTGDR2 (1.00) | PTGDR2AKR1B1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2219645-A2 | USE OF CRTH2 ANTAGONIST COMPOUNDS | Oxagen Limited (GB) | 2010-08-25 | — | — | EP | claimed |
| WO-2009063202-A2 | USE OF CRTH2 ANTAGONIST COMPOUNDS | OXAGEN LIMITED (GB) | 2009-05-22 | — | — | WO | claimed |