⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39037 | 0.72 | — | — | |
| SCHEMBL29203160 | 0.72 | — | — | |
| SCHEMBL5691354 | 0.67 | — | — | |
| SCHEMBL5463883 | 0.67 | — | — | |
| SCHEMBL6021901 | 0.67 | — | — | |
| SCHEMBL8088339 | 0.67 | — | — | |
| SCHEMBL9118127 | 0.65 | — | — | |
| SCHEMBL352978 | 0.65 | — | — | |
| SCHEMBL9118123 | 0.65 | — | — | |
| SCHEMBL5956027 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 319 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240240226-A1 | FLUOROGENIC ASSAY FOR RAPID SCREENING OF BACTERIAL BETA-LACTAMASE ACTIVITY | UNIV LELAND STANFORD JUNIOR (US) | 2024-07-18 | — | — | US | disclosed |
| WO-2023237097-A1 | 19-NOR-C3,3-DISUBSTITUTED C21-AZACYCLO-SUBSTITUTED STEROID AND METHOD FOR USING SAME | 山东绿叶制药有限公司 | 2023-12-14 | — | — | WO | disclosed |
| WO-2023278986-A1 | SILENT AGONISTS OF ALPHA7- AND ALPHA9-CONTAINING NICOTINIC ACETYLCHOLINE RECEPTORS FOR REDUCING NEUROPATHIC AND INFLAMMATORY PAIN | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2023-01-05 | — | — | WO | disclosed |
| US-20210332046-A1 | NICOTINIC ACETYLCHOLINE RECEPTOR SILENT AGONISTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-10-28 | — | — | US | disclosed |
| US-11155551-B2 | Nicotinic acetylcholine receptor silent agonists | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2021-10-26 | — | — | US | disclosed |
| US-20200247804-A1 | NICOTINIC ACETYLCHOLINE RECEPTOR SILENT AGONISTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2020-08-06 | — | — | US | disclosed |
| US-10730840-B2 | Substituted tetrahydroisoquinoline ethylbenzamide anti-cancer agents | FLORIDA A&M UNIVERSITY (US) | 2020-08-04 | — | — | US | disclosed |
| US-10675364-B2 | Rhodol fluorophores for near-infrared imaging | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-06-09 | — | — | US | disclosed |
| US-10675366-B2 | Imaging tumor glycolysis by non-invasive measurement of pyruvate kinase M2 | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-06-09 | — | — | US | disclosed |
| US-10662191-B2 | Nicotinic acetylcholine receptor silent agonists | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INC. (US) | 2020-05-26 | — | — | US | disclosed |
| EP-0777660-A1 | NOVEL ALKYLAMINO DERIVATIVES AS SIGMA 2 SELECTIVE LIGANDS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996005185-A1 | NOVEL ALKYLAMINO DERIVATIVES AS SIGMA 2 SELECTIVE LIGANDS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-02-22 | — | — | WO | disclosed |
| EP-0281103-B1 | PHENOXYCARBOXYLIC ACID COMPOUNDS AND HERBICIDE COMPRISING IT AS ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1993-06-23 | — | — | EP | disclosed |
| EP-0533925-A1 | OPTICAL ISOMER OF R-FORM OF DIPHENYL ETHER DERIVATIVE AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1993-03-31 | — | — | EP | disclosed |
| EP-0442172-A1 | Oxime derivatives and Herbicides containing the same as an active ingredient | TEIJIN LIMITED (JP) | 1991-08-21 | — | — | EP | disclosed |
| EP-0433451-A1 | OXIME DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS AN ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1991-06-26 | — | — | EP | disclosed |
| WO-1990001874-A1 | OXIME DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS AN ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1990-03-08 | — | — | WO | disclosed |
| US-4845264-A | PRE- AND POST-EMERGENCE FOR BROAD-LEAVED WEEDS | TEIJIN LIMITED (JP) | 1989-07-04 | — | — | US | disclosed |
| US-4801750-A | Process for the produciton of 2-chloroacetoacetic acid amides | LONZA LTD. (CH) | 1989-01-31 | — | — | US | disclosed |
| EP-0281103-A2 | Phenoxycarboxylic acid compounds and herbicide comprising it as active ingredient | TEIJIN LIMITED (JP) | 1988-09-07 | — | — | EP | disclosed |