Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26636891 | 1.00 | NR1H2 (0.47) | NR1H2NAMPTUSP2SMN1; SMN2GPR119 | |
| SCHEMBL10220897 | 1.00 | NR1H2 (0.47) | NR1H2NAMPTUSP2SMN1; SMN2GPR119 | |
| SCHEMBL335294 | 1.00 | NR1H2 (0.47) | NR1H2NAMPTUSP2SMN1; SMN2GPR119 | |
| SCHEMBL30115827 | 0.91 | NR1H2 (0.49) | NR1H2NAMPTUSP2SMN1; SMN2GPR119 | |
| SCHEMBL30390162 | 0.88 | NR1H2 (0.40) | NR1H2NAMPTUSP2SMN1; SMN2GPR119 | |
| SCHEMBL13744392 | 0.85 | NR1H2 (0.44) | NR1H2NAMPTUSP2SMN1; SMN2GPR119 | |
| SCHEMBL30199567 | 0.85 | NR1H2 (0.44) | NR1H2NAMPTUSP2SMN1; SMN2GPR119 | |
| SCHEMBL30338313 | 0.84 | NR1H2 (0.49) | NR1H2NAMPTUSP2SMN1; SMN2GPR119 | |
| SCHEMBL30778455 | 0.84 | NR1H2 (0.49) | NR1H2NAMPTUSP2SMN1; SMN2GPR119 | |
| SCHEMBL3315088 | 0.81 | NR1H2 (0.40) | NR1H2USP2SMN1; SMN2GPR119EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715903-A | Cereblon binding compounds, compositions thereof, and methods for their use in therapy | 新基公司 | 2024-03-15 | — | — | CN | disclosed |