Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.60 |
| ▸ | DDB1 | Q16531 | 18/20 | 0.60 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30826021 | 1.00 | CRBN (0.60) | CRBNDDB1IKZF3CYP19A1 | |
| Hydrochloric Acid SCHEMBL29170247 | 0.98 | CRBN (0.59) | CRBNDDB1IKZF3CYP19A1 | |
| Hydrochloric Acid SCHEMBL30826004 | 0.98 | CRBN (0.59) | CRBNDDB1IKZF3CYP19A1 | |
| SCHEMBL26296852 | 0.82 | CRBN (0.60) | CRBNDDB1 | |
| SCHEMBL30475499 | 0.82 | CRBN (0.60) | CRBNDDB1 | |
| SCHEMBL24832952 | 0.82 | CRBN (0.60) | CRBNDDB1 | |
| SCHEMBL26296953 | 0.82 | CRBN (0.60) | CRBNDDB1 | |
| SCHEMBL25819560 | 0.82 | CRBN (0.60) | CRBNDDB1 | |
| SCHEMBL31103386 | 0.81 | CRBN (0.56) | CRBNDDB1 | |
| SCHEMBL25074998 | 0.78 | CRBN (0.56) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715903-A | Cereblon binding compounds, compositions thereof, and methods for their use in therapy | 新基公司 | 2024-03-15 | — | — | CN | disclosed |