Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29170260 | 1.00 | NR1H2 (0.38) | NR1H2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL26637383 | 0.88 | NR1H2 (0.36) | NR1H2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL26636215 | 0.88 | NR1H2 (0.36) | NR1H2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL26636218 | 0.88 | NR1H2 (0.36) | NR1H2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28973117 | 0.87 | NR1H2 (0.40) | NR1H2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28973115 | 0.87 | NR1H2 (0.40) | NR1H2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28973193 | 0.87 | NR1H2 (0.40) | NR1H2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL24876558 | 0.84 | NR1H2 (0.41) | NR1H2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28973235 | 0.84 | TACR1 (0.33) | — | |
| SCHEMBL28973238 | 0.84 | TACR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715903-A | Cereblon binding compounds, compositions thereof, and methods for their use in therapy | 新基公司 | 2024-03-15 | — | — | CN | disclosed |