Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | MLKL | Q8NB16 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30848269 | 1.00 | HSP90AA1 (0.53) | HSP90AA1ESR2TDP1GRIK1GRIA1 | |
| SCHEMBL30799117 | 0.90 | CHEK2 (0.43) | HSP90AA1ESR2TDP1CHEK2 | |
| SCHEMBL29172032 | 0.90 | CHEK2 (0.43) | HSP90AA1ESR2TDP1CHEK2 | |
| SCHEMBL30798800 | 0.88 | TLR8 (0.43) | HSP90AA1ESR2TDP1ALDH1A1HPGD | |
| SCHEMBL29171974 | 0.88 | BRD4 (0.48) | HSP90AA1ESR2TDP1ALDH1A1HPGD | |
| SCHEMBL30798804 | 0.83 | TDP1 (0.58) | HSP90AA1ESR2TDP1GRIK1GRIA1 | |
| SCHEMBL29171880 | 0.83 | TDP1 (0.58) | HSP90AA1ESR2TDP1GRIK1GRIA1 | |
| SCHEMBL29171943 | 0.82 | BRD4 (0.47) | POLBRAB9ASMN1; SMN2TRPV1BRD4 | |
| SCHEMBL30848037 | 0.82 | BRD4 (0.47) | POLBRAB9ASMN1; SMN2TRPV1BRD4 | |
| SCHEMBL30848167 | 0.80 | HSP90AA1 (0.54) | HSP90AA1ESR2TDP1GRIK1GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720472-A | Benzimidazole compound, and preparation method and application thereof | 苏州沪云新药研发股份有限公司 | 2024-03-19 | — | — | CN | disclosed |