SCHEMBL2917482

SCHEMBL2917482

c1ccc(Cn2cncn2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 10/20 1.00
HDAC1 Q13547 2/20 0.54
HDAC6 Q9UBN7 2/20 0.54
HSP90AA1 P07900 1/20 0.51
LMNA P02545 2/20 0.51
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
TP53 P04637 1/20 0.50
MAPT P10636 1/20 0.50
NFKB1 P19838 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9382670 0.98 CYP19A1 (0.96) CYP19A1HDAC1HDAC6HSP90AA1LMNA
SCHEMBL9023539 0.93 CYP19A1 (0.86) CYP19A1HDAC1HDAC6HSP90AA1LMNA
SCHEMBL17159812 0.89 CYP19A1 (0.80) CYP19A1HDAC1HDAC6
SCHEMBL7674570 0.89 CYP19A1 (0.79) CYP19A1HDAC1HDAC6LMNASMN1; SMN2
SCHEMBL10172554 0.84 CYP19A1 (1.00) CYP19A1HDAC1HDAC6
SCHEMBL3235402 0.84 NPC1 (0.72) CYP19A1HDAC6LMNANPC1RAB9A
SCHEMBL31415773 0.84 CYP19A1 (0.71) CYP19A1NPC1RAB9A
SCHEMBL15688800 0.83 CYP19A1 (0.71) CYP19A1HDAC1HDAC6
SCHEMBL305828 0.83 CYP19A1 (0.97) CYP19A1HDAC1HDAC6LMNAMAPT
SCHEMBL3235365 0.82 CYP19A1 (0.69) CYP19A1HDAC1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12011708-B2 Organic frame material having cobalt-containing isopoly-molybdic acid metal, method of manufacturing the same, and application thereof Changzhou University (CN) 2024-06-18 US claimed
US-20230167236-A1 ORGANIC FRAME MATERIAL HAVING ISOPOLY-MOLYBDIC ACID METAL FOR MANUFACTURING POLYLACTIC ACID AND METHOD OF MANUFACTURING THE SAME Changzhou University (CN) 2023-06-01 US claimed
US-20230158477-A1 ORGANIC FRAME MATERIAL HAVING COBALT-CONTAINING ISOPOLY-MOLYBDIC ACID METAL, METHOD OF MANUFACTURING THE SAME, AND APPLICATION THEREOF Changzhou University (CN) 2023-05-25 US claimed
US-20230159699-A1 ORGANIC FRAME MATERIAL HAVING ZINC CONTAINING ISO-MOLYBDIC ACID METAL, METHOD OF MANUFACTURING THE SAME, AND APPLICATION THEREOF Changzhou University (CN) 2023-05-25 US claimed
CN-113956499-B Zinc-containing isopolymolybdic acid metal organic framework material and preparation method and application thereof 常州大学 2022-11-11 CN claimed
CN-110878102-B Bis-triazole ligand regulated 5-nitroisophthalic acid cadmium complex, preparation method thereof and application thereof as fluorescent probe 衡阳师范学院 2022-05-24 CN claimed
CN-113999401-B Cobalt-containing isopolymolybdic acid metal organic framework material and preparation method and application thereof 常州大学 2022-05-20 CN claimed
CN-113929924-B Isopolymolybdic acid metal organic framework material for preparing polylactic acid and preparation method 常州大学 2022-04-22 CN claimed
CN-113999401-A Cobalt-containing isopolymolybdic acid metal organic framework material and preparation method and application thereof 常州大学 2022-02-01 CN claimed
CN-113956499-A Zinc-containing isopolymolybdic acid metal organic framework material and preparation method and application thereof 常州大学 2022-01-21 CN claimed
CN-107556465-B Zinc coordination polymer and preparation method with catalyzing ring-opening polymerization of lactide performance 常州大学 2019-11-12 CN claimed
CN-109721586-A A kind of 5- benzyl -3- pyridyl group -1H-1,2,4- triazole class compounds and its preparation method and application 中国医科大学 2019-05-07 CN claimed
CN-107556465-A Zinc coordination polymer and preparation method with catalyzing ring-opening polymerization of lactide performance 常州大学 2018-01-09 CN claimed
CN-107556485-A A kind of cobalt coordination polymer material and its preparation method and application 常州大学 2018-01-09 CN claimed
CN-107501535-A Zn complex catalyst of PLA and preparation method thereof is prepared for ring-opening polymerisation 常州大学 2017-12-22 CN claimed
CN-105820182-A Thermal stable copper metal organic framework material and preparation method and application thereof 常州大学 2016-08-03 CN claimed
CN-103539805-B A kind of CuCN complex based on flexible dual-triazole ligand and preparation method thereof ANQING NORMAL UNIVERSITY (CN) 2016-01-20 CN claimed
CN-103664811-B (1H-1,2,4-triazol-1-yl) aryl compound and preparation method thereof IHARA CHEMICAL IND CO. (JP) 2015-09-16 CN claimed
CN-103664811-A Aryl (1h-1,2,4-triazol-1-yl) compound, and process for production thereof IHARA CHEMICAL IND CO 2014-03-26 CN claimed
CN-101910140-A (1H-1,2, 4-triazol-1-yl) aryl compounds and process for producing the same IHARA CHEMICAL IND CO 2010-12-08 CN claimed