SCHEMBL29175263

SCHEMBL29175263

CCCCCCCC(CCCCCCC)OC(=O)CCCC(O)CCCC(=O)O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.68
FFAR1 O14842 2/20 0.68
MAPK1 P28482 5/20 0.53
MAPT P10636 4/20 0.53
GPR84 Q9NQS5 4/20 0.51
LMNA P02545 4/20 0.50
GMNN O75496 3/20 0.50
NPSR1 Q6W5P4 3/20 0.50
CYP1A2 P05177 2/20 0.50
MEN1 O00255 2/20 0.50
HSP90AA1 P07900 2/20 0.50
BLM P54132 2/20 0.50
KMT2A Q03164 2/20 0.50
NR1H4 Q96RI1 2/20 0.50
ALDH1A1 P00352 1/20 0.50
TP53 P04637 1/20 0.50
CYP2C9 P11712 1/20 0.50
TSHR P16473 1/20 0.50
HIF1A Q16665 1/20 0.50
GLA P06280 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15692650 0.97 FFAR4 (0.73) FFAR4FFAR1MAPK1MAPTGPR84
SCHEMBL1134727 0.97 FFAR4 (0.73) FFAR4FFAR1MAPK1MAPTGPR84
SCHEMBL3403797 0.95 FFAR4 (0.66) FFAR4FFAR1MAPK1MAPTGPR84
SCHEMBL29160513 0.94 FFAR4 (0.69) FFAR4FFAR1MAPK1MAPTGPR84
SCHEMBL24715381 0.94 MAPT (0.59) FFAR4FFAR1MAPK1MAPTGPR84
SCHEMBL10695256 0.93 FFAR4 (0.66) FFAR4FFAR1MAPK1MAPTGPR84
SCHEMBL26100264 0.92 MAPK1 (0.62) FFAR4FFAR1MAPK1MAPTGPR84
SCHEMBL16063632 0.92 MAPK1 (0.62) FFAR4FFAR1MAPK1MAPTGPR84
SCHEMBL25432635 0.92 MAPK1 (0.62) FFAR4FFAR1MAPK1MAPTGPR84
SCHEMBL23860683 0.91 MAPK1 (0.64) FFAR4FFAR1MAPK1MAPTGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117715886-A Ionizable cationic lipids for RNA delivery 阿克丘勒斯治疗公司 2024-03-15 CN disclosed