Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 4/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7559310 | 0.85 | KMT2A (0.53) | SMN1; SMN2KMT2AKDM4EALDH1A1TP53 | |
| SCHEMBL10527677 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2AKDM4EALDH1A1ABCB1 | |
| SCHEMBL2518861 | 0.82 | SMN1; SMN2 (0.68) | SMN1; SMN2KMT2AKDM4EALDH1A1TP53 | |
| SCHEMBL16953073 | 0.82 | KMT2A (0.51) | SMN1; SMN2KMT2AKDM4EALDH1A1TP53 | |
| SCHEMBL12844409 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AKDM4EALDH1A1BCHE | |
| SCHEMBL1254107 | 0.79 | KMT2A (0.55) | SMN1; SMN2KMT2AKDM4EALDH1A1BCHE | |
| SCHEMBL1254108 | 0.79 | TAAR1 (0.61) | SMN1; SMN2KMT2AABCB1 | |
| SCHEMBL12775752 | 0.79 | KMT2A (0.46) | SMN1; SMN2KMT2AKDM4EALDH1A1TP53 | |
| SCHEMBL2525316 | 0.79 | SMN1; SMN2 (0.63) | SMN1; SMN2KMT2AKDM4EALDH1A1GSK3A | |
| SCHEMBL20551900 | 0.78 | KMT2A (0.48) | SMN1; SMN2KMT2AKDM4EALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117587078-A | Preparation method of apremilast drug intermediate | 华中科技大学 | 2024-02-23 | — | — | CN | disclosed |