⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22293869 | 0.76 | — | — | |
| SCHEMBL27600526 | 0.66 | PRCP (0.53) | — | |
| SCHEMBL15932155 | 0.62 | — | — | |
| SCHEMBL27559419 | 0.56 | — | — | |
| SCHEMBL28193627 | 0.56 | — | — | |
| SCHEMBL8289297 | 0.55 | — | — | |
| SCHEMBL27314712 | 0.54 | — | — | |
| SCHEMBL27303333 | 0.54 | — | — | |
| SCHEMBL27306416 | 0.54 | — | — | |
| SCHEMBL27457152 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114262290-B | 4-methylene pyrrolidine-2-thioketone compound, and synthetic method and application thereof | 华东师范大学 | 2024-03-22 | — | — | CN | claimed |
| CN-114262290-A | 4-methylene pyrrolidine-2-thioketone compound and synthesis method and application thereof | 华东师范大学 | 2022-04-01 | — | — | CN | claimed |
| CN-114262290-B | 4-methylene pyrrolidine-2-thioketone compound, and synthetic method and application thereof | 华东师范大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-114262290-B | 4-methylene pyrrolidine-2-thioketone compound, and synthetic method and application thereof | 华东师范大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-114262290-B | 4-methylene pyrrolidine-2-thioketone compound, and synthetic method and application thereof | 华东师范大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-114262290-A | 4-methylene pyrrolidine-2-thioketone compound and synthesis method and application thereof | 华东师范大学 | 2022-04-01 | — | — | CN | disclosed |
| CN-114262290-A | 4-methylene pyrrolidine-2-thioketone compound and synthesis method and application thereof | 华东师范大学 | 2022-04-01 | — | — | CN | disclosed |
| CN-114262290-A | 4-methylene pyrrolidine-2-thioketone compound and synthesis method and application thereof | 华东师范大学 | 2022-04-01 | — | — | CN | disclosed |