Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KATNA1 | O75449 | 1/20 | 0.52 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.41 |
| ▸ | TUBB | P07437 | 5/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30800001 | 1.00 | KATNA1 (0.52) | KATNA1MKNK2TUBB4ATUBBTUBA3C | |
| SCHEMBL29176287 | 0.87 | KATNA1 (0.50) | KATNA1MKNK2TUBB4ATUBBTUBA3C | |
| SCHEMBL30800071 | 0.87 | KATNA1 (0.50) | KATNA1MKNK2TUBB4ATUBBTUBA3C | |
| SCHEMBL29176288 | 0.87 | KATNA1 (0.50) | KATNA1MKNK2TUBB4ATUBBTUBA3C | |
| SCHEMBL28474690 | 0.85 | KATNA1 (0.49) | KATNA1MKNK2TUBB4ATUBBTUBA3C | |
| SCHEMBL30799997 | 0.84 | KATNA1 (0.54) | KATNA1MKNK2TUBB4ATUBBTUBA3C | |
| SCHEMBL29176273 | 0.84 | KATNA1 (0.54) | KATNA1MKNK2TUBB4ATUBBTUBA3C | |
| SCHEMBL29176281 | 0.80 | KATNA1 (0.64) | KATNA1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30800023 | 0.80 | KATNA1 (0.64) | KATNA1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30799979 | 0.70 | BLK (0.46) | KATNA1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111732584-B | Diaryl substituted fused heterocycle compound and preparation method and application thereof in pharmacy | 复旦大学 | 2024-02-27 | — | — | CN | disclosed |