Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 8/20 | 1.00 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 1.00 |
| ▸ | CDK2 | P24941 | 3/20 | 0.72 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.72 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.72 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.70 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.60 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.60 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.59 |
| ▸ | IDO1 | P14902 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.57 |
| ▸ | WNT3A | P56704 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30695138 | 1.00 | FLT3 (1.00) | FLT3MAP4K1CDK2CCNA2CCNA1 | |
| SCHEMBL30398090 | 0.84 | FLT3 (1.00) | FLT3MAP4K1CDK2CCNA2CCNA1 | |
| SCHEMBL951125 | 0.84 | FLT3 (1.00) | FLT3MAP4K1CDK2CCNA2CCNA1 | |
| SCHEMBL30695127 | 0.84 | FLT3 (0.73) | FLT3MAP4K1CDK2CCNA2CCNA1 | |
| SCHEMBL30695136 | 0.84 | FLT3 (0.73) | FLT3MAP4K1CDK2CCNA2CCNA1 | |
| SCHEMBL29176630 | 0.84 | FLT3 (0.73) | FLT3MAP4K1CDK2CCNA2CCNA1 | |
| SCHEMBL953507 | 0.84 | FLT3 (0.73) | FLT3MAP4K1CDK2CCNA2CCNA1 | |
| SCHEMBL30695135 | 0.84 | FLT3 (0.73) | FLT3MAP4K1CDK2CCNA2CCNA1 | |
| SCHEMBL29176618 | 0.84 | FLT3 (0.73) | FLT3MAP4K1CDK2CCNA2CCNA1 | |
| SCHEMBL31705956 | 0.84 | FLT3 (0.76) | FLT3MAP4K1CDK2CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024109642-A1 | USE OF BENZOAZACYCLIC COMPOUND AS ALLOSTERIC MODULATOR OF β2-ADRENOCEPTOR | 常州大学 | 2024-05-30 | — | — | WO | disclosed |
| CN-117229217-A | Allosteric modulator of adrenergic receptor functional activity, preparation method and application thereof | 常州大学 | 2023-12-15 | — | — | CN | disclosed |