Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.34 |
| ▸ | CDK1 | P06493 | 2/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30739154 | 1.00 | PDE5A (0.39) | PDE5AKDM4EMAPTPOLBBLM | |
| SCHEMBL30739279 | 0.93 | CYP3A4 (0.38) | PDE5AKDM4EMAPTPOLBBLM | |
| SCHEMBL30739277 | 0.87 | PDE5A (0.38) | PDE5AKDM4EMAPTPOLBBLM | |
| SCHEMBL30739341 | 0.86 | ALOX5AP (0.38) | PDE5AKDM4EMAPTPOLBBLM | |
| SCHEMBL30739241 | 0.86 | PDE5A (0.37) | PDE5AKDM4EMAPTPOLBBLM | |
| SCHEMBL30739143 | 0.85 | PDE5A (0.36) | PDE5AKDM4EMAPTPOLBBLM | |
| SCHEMBL30739174 | 0.85 | CYP3A4 (0.37) | PDE5AKDM4EMAPTPOLBBLM | |
| SCHEMBL30739246 | 0.85 | PDE5A (0.35) | PDE5AKDM4EMAPTPOLBBLM | |
| SCHEMBL29178868 | 0.85 | PDE5A (0.45) | PDE5AKDM4EMAPTPOLBBLM | |
| SCHEMBL29178870 | 0.84 | KDM4E (0.43) | PDE5AKDM4EMAPTPOLBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466897-A | Highly selective FGFR2 inhibitors | 深圳福沃药业有限公司 | 2024-01-30 | — | — | CN | disclosed |