Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | PDE5A | O76074 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30739169 | 0.89 | EGFR (0.40) | EGFRPOLBNR2F2LMNATP53 | |
| SCHEMBL29178907 | 0.89 | EGFR (0.40) | EGFRPOLBNR2F2LMNATP53 | |
| SCHEMBL29178629 | 0.89 | EGFR (0.41) | EGFRPOLBNR2F2LMNATP53 | |
| SCHEMBL29178634 | 0.89 | EGFR (0.39) | EGFRPOLBNR2F2LMNATP53 | |
| SCHEMBL30739218 | 0.89 | EGFR (0.39) | EGFRPOLBNR2F2LMNATP53 | |
| SCHEMBL29178752 | 0.88 | AURKA (0.41) | EGFRPOLBNR2F2LMNATP53 | |
| SCHEMBL29178699 | 0.88 | EGFR (0.39) | EGFRPOLBNR2F2LMNATP53 | |
| SCHEMBL30739343 | 0.88 | EGFR (0.39) | EGFRPOLBNR2F2LMNATP53 | |
| SCHEMBL29178646 | 0.88 | EGFR (0.39) | EGFRPOLBNR2F2LMNATP53 | |
| SCHEMBL29178790 | 0.86 | MAPT (0.40) | EGFRPOLBNR2F2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466897-A | Highly selective FGFR2 inhibitors | 深圳福沃药业有限公司 | 2024-01-30 | — | — | CN | disclosed |