Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 7/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | ATP4A | P20648 | 1/20 | 0.31 |
| ▸ | ATP4B | P51164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30739350 | 1.00 | CYP19A1 (0.34) | CYP19A1CYP11B1CYP11B2PTGER1ERN1 | |
| SCHEMBL29178783 | 0.90 | ERN1 (0.38) | CYP19A1CYP11B1CYP11B2PTGER1ERN1 | |
| SCHEMBL29178855 | 0.89 | PTGER1 (0.34) | CYP19A1CYP11B1CYP11B2PTGER1ERN1 | |
| SCHEMBL30739319 | 0.89 | PTGER1 (0.34) | CYP19A1CYP11B1CYP11B2PTGER1ERN1 | |
| SCHEMBL29178900 | 0.88 | MRGPRX4 (0.33) | CYP19A1CYP11B1CYP11B2PTGER1ERN1 | |
| SCHEMBL30739285 | 0.88 | MRGPRX4 (0.33) | CYP19A1CYP11B1CYP11B2PTGER1ERN1 | |
| SCHEMBL29178946 | 0.87 | KDM1A (0.35) | PTGER1ERN1S1PR5MRGPRX4KDM1A | |
| SCHEMBL30739338 | 0.86 | ERN1 (0.36) | CYP19A1CYP11B1CYP11B2PTGER1ERN1 | |
| SCHEMBL29178786 | 0.86 | ERN1 (0.36) | CYP19A1CYP11B1CYP11B2PTGER1ERN1 | |
| SCHEMBL29178634 | 0.83 | EGFR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466897-A | Highly selective FGFR2 inhibitors | 深圳福沃药业有限公司 | 2024-01-30 | — | — | CN | disclosed |