SCHEMBL29180738

SCHEMBL29180738

O=C1CN([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C(=S)NC1=O

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CDA P32320 9/20 0.54
▸ SLC28A1 O00337 1/20 0.42
▸ SLC28A2 O43868 1/20 0.42
▸ SLC29A1 Q99808 1/20 0.42
▸ SLC28A3 Q9HAS3 1/20 0.42
▸ MAPT P10636 1/20 0.40
▸ PYGM P11217 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29047907 0.89 CDA (0.55) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL7705298 0.81 CDA (0.54) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL15010376 0.78 CDA (0.54) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL15010708 0.76 CDA (0.52) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL15011257 0.76 CDA (0.52) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL10859054 0.75 CDA (0.52) CDASLC28A1SLC28A2SLC29A1SLC28A3
Uridine SCHEMBL29002276 0.75 SLC28A1 (0.73) SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL21832053 0.74 CDA (0.50) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL6015184 0.72 CDA (0.66) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL399314 0.72 CDA (0.66) CDASLC28A1SLC28A2SLC29A1SLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117580950-A Compositions and methods for treating TDP-43 proteinopathies 梅兹治疗公司 2024-02-20 — — CN disclosed
Send feedback