Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FURIN | P09958 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21133185 | 1.00 | KMT2A (0.43) | KMT2AMEN1GAATAS1R3TAS1R1 | |
| SCHEMBL21133184 | 1.00 | KMT2A (0.43) | KMT2AMEN1GAATAS1R3TAS1R1 | |
| SCHEMBL29755156 | 1.00 | KMT2A (0.43) | KMT2AMEN1GAATAS1R3TAS1R1 | |
| SCHEMBL21132427 | 0.91 | KMT2A (0.52) | KMT2AMEN1GAACES2LMNA | |
| SCHEMBL20792450 | 0.91 | KMT2A (0.52) | KMT2AMEN1GAACES2LMNA | |
| SCHEMBL22321401 | 0.91 | KMT2A (0.52) | KMT2AMEN1GAACES2LMNA | |
| SCHEMBL29949168 | 0.91 | KMT2A (0.52) | KMT2AMEN1GAACES2LMNA | |
| SCHEMBL24943389 | 0.87 | KMT2A (0.40) | KMT2AMEN1GAAACHECES2 | |
| SCHEMBL23578370 | 0.87 | KMT2A (0.40) | KMT2AMEN1GAAACHECES2 | |
| SCHEMBL23578368 | 0.87 | KMT2A (0.40) | KMT2AMEN1GAAACHECES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117580836-A | Pyrimidine ring structure derivative and application thereof | 四川汇宇制药股份有限公司 | 2024-02-20 | — | — | CN | disclosed |