Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.76 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.76 |
| ▸ | FAP | Q12884 | 3/20 | 0.70 |
| ▸ | POU2F2 | P09086 | 1/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.70 |
| ▸ | POU2F1 | P14859 | 1/20 | 0.70 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.70 |
| ▸ | HRH2 | P25021 | 1/20 | 0.70 |
| ▸ | MC4R | P32245 | 1/20 | 0.70 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.70 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.70 |
| ▸ | GHSR | Q92847 | 1/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4813348 | 0.87 | DPP4 (0.78) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL5842437 | 0.87 | DPP4 (1.00) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL4813357 | 0.87 | DPP4 (0.78) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL5842422 | 0.87 | DPP4 (1.00) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL8351902 | 0.84 | DPP4 (0.88) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL4808547 | 0.84 | DPP4 (0.74) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL4808537 | 0.84 | DPP4 (0.74) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL196653 | 0.82 | DPP4 (1.00) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| Linagliptin SCHEMBL17124941 | 0.82 | DPP4 (1.00) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL196652 | 0.82 | DPP4 (1.00) | DPP4CHRM1FAPPOU2F2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2023902-B1 | DPP IV INHIBITOR FORMULATIONS | BOEHRINGER INGELHEIM INT (DE) | 2010-09-08 | — | — | EP | claimed |