Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29181544 | 0.93 | DHODH (0.36) | DHODHTRPA1AVPR1AMALT1GPBAR1 | |
| SCHEMBL29181578 | 0.92 | DHODH (0.37) | DHODHTRPA1AVPR1AMALT1TRPV1 | |
| SCHEMBL24397797 | 0.92 | DHODH (0.37) | DHODHTRPA1AVPR1AMALT1RBP4 | |
| SCHEMBL29181560 | 0.92 | DHODH (0.37) | DHODHTRPA1AVPR1AMALT1RBP4 | |
| SCHEMBL29129837 | 0.91 | DHODH (0.36) | DHODHTRPA1AVPR1AMALT1RBP4 | |
| SCHEMBL28457040 | 0.90 | DHODH (0.36) | DHODHTRPA1AVPR1AMALT1RBP4 | |
| SCHEMBL24397959 | 0.90 | DHODH (0.39) | DHODHMALT1RBP4TRPV1 | |
| SCHEMBL24397881 | 0.89 | DHODH (0.35) | DHODHCNR2 | |
| SCHEMBL28451016 | 0.89 | DHODH (0.35) | DHODHTRPA1AVPR1A | |
| SCHEMBL28455371 | 0.89 | DHODH (0.35) | DHODHTRPA1AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263908-A | Preparation of 1-pyridylpyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-117263908-A | Preparation of 1-pyridylpyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-22 | — | — | CN | disclosed |