Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29181580 | 0.95 | DHODH (0.34) | DHODHS1PR1TRPA1 | |
| SCHEMBL29181575 | 0.95 | DHODH (0.35) | DHODHTRPA1KDM4EMEN1ALDH1A1 | |
| SCHEMBL29181588 | 0.93 | DHODH (0.34) | DHODHS1PR1TRPA1S1PR3OPRK1 | |
| SCHEMBL29181521 | 0.93 | DHODH (0.34) | DHODHS1PR1 | |
| Hydrochloric Acid SCHEMBL29181593 | 0.92 | DHODH (0.34) | DHODHS1PR1TRPA1S1PR3 | |
| SCHEMBL29181526 | 0.91 | DHODH (0.36) | DHODHTRPA1KDM4EMEN1ALDH1A1 | |
| SCHEMBL29181537 | 0.90 | DHODH (0.34) | DHODHS1PR1 | |
| SCHEMBL29181545 | 0.90 | DHODH (0.34) | DHODHTRPA1 | |
| SCHEMBL29181534 | 0.88 | DHODH (0.34) | DHODHS1PR1TRPA1S1PR3 | |
| SCHEMBL29181558 | 0.88 | DHODH (0.35) | DHODHTRPA1KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263908-A | Preparation of 1-pyridylpyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-117263908-A | Preparation of 1-pyridylpyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-22 | — | — | CN | disclosed |