Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.70 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.64 |
| ▸ | MAOA | P21397 | 2/20 | 0.63 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.57 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29014213 | 1.00 | MAOB (0.70) | MAOBABCG2MAOACXCL12CYSLTR2 | |
| SCHEMBL29014219 | 0.97 | MAOB (0.70) | MAOBABCG2MAOACXCL12CYSLTR2 | |
| SCHEMBL29014252 | 0.88 | MAOB (0.71) | MAOBABCG2MAOAHRH3BCHE | |
| SCHEMBL29181747 | 0.88 | MAOB (0.71) | MAOBABCG2MAOAHRH3BCHE | |
| SCHEMBL2990656 | 0.87 | MAOB (0.70) | MAOBABCG2HRH3BCHEACHE | |
| SCHEMBL2995394 | 0.87 | MAOB (0.70) | MAOBABCG2HRH3BCHEACHE | |
| SCHEMBL31463109 | 0.87 | MAOB (0.71) | MAOBABCG2MAOABCHECYP1B1 | |
| SCHEMBL2990657 | 0.87 | MAOB (0.70) | MAOBABCG2HRH3BCHEACHE | |
| SCHEMBL2995392 | 0.87 | MAOB (0.70) | MAOBABCG2HRH3BCHEACHE | |
| SCHEMBL29014271 | 0.87 | MAOB (0.71) | MAOBABCG2MAOAHRH3BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954731-A | Chalcone derivative containing 4-quinazolinone structure, and preparation method and application thereof | 黔南州烟草公司平塘县分公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-117645567-A | Chalcone derivative containing piperidine sulfonamide structure, and preparation method and application thereof | 贵州大学 | 2024-03-05 | — | — | CN | disclosed |