Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 13/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30363778 | 1.00 | CD38 (0.53) | CD38CYP2D6CYP2B6CYP2C19TNKS | |
| SCHEMBL25136045 | 1.00 | CD38 (0.53) | CD38CYP2D6CYP2B6CYP2C19TNKS | |
| SCHEMBL29182287 | 0.88 | CD38 (0.56) | CD38CYP2D6CYP2B6CYP2C19 | |
| SCHEMBL25135933 | 0.88 | CD38 (0.56) | CD38CYP2D6CYP2B6CYP2C19 | |
| SCHEMBL29182213 | 0.87 | CD38 (0.45) | CD38CYP2D6CYP2B6CYP2C19TNKS | |
| SCHEMBL25135938 | 0.87 | CD38 (0.45) | CD38CYP2D6CYP2B6CYP2C19TNKS | |
| SCHEMBL30363702 | 0.87 | CD38 (0.45) | CD38CYP2D6CYP2B6CYP2C19TNKS | |
| SCHEMBL25136104 | 0.86 | CD38 (0.43) | CD38CYP2D6CYP2B6CYP2C19TNKS | |
| SCHEMBL30363646 | 0.86 | CD38 (0.43) | CD38CYP2D6CYP2B6CYP2C19TNKS | |
| SCHEMBL29182226 | 0.86 | CD38 (0.43) | CD38CYP2D6CYP2B6CYP2C19TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813296-A | CD38 modulators and methods of use thereof | 赛特凯恩蒂克公司 | 2024-04-02 | — | — | CN | disclosed |