SCHEMBL29183147

SCHEMBL29183147

FC(F)(F)C(F)(F)C(F)(F)c1cnc2ccccc2n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.41
ELANE P08246 1/20 0.41
KDM4E B2RXH2 4/20 0.38
GPR3 P46089 1/20 0.38
ALDH1A1 P00352 4/20 0.38
HPGD P15428 3/20 0.38
HSD17B10 Q99714 2/20 0.38
ALOX15 P16050 1/20 0.38
HTT P42858 5/20 0.37
PDGFRB P09619 1/20 0.37
PDGFRA P16234 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MAPT P10636 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
BCHE P06276 1/20 0.36
GAA P10253 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29183172 0.89 PDE10A (0.44) PDE10AELANEKDM4EGPR3ALDH1A1
SCHEMBL29764247 0.80 PDE10A (0.47) PDE10AKDM4EGPR3ALDH1A1HPGD
SCHEMBL1671064 0.80 PDE10A (0.47) PDE10AKDM4EGPR3ALDH1A1HPGD
Hydrochloric Acid SCHEMBL4574425 0.79 PDE10A (0.45) PDE10AKDM4EGPR3ALDH1A1HPGD
Methane SCHEMBL28258530 0.79 PDE10A (0.45) PDE10AKDM4EGPR3ALDH1A1HPGD
SCHEMBL18661272 0.77 PDE10A (0.44) PDE10AKDM4EGPR3ALDH1A1HPGD
SCHEMBL29183155 0.77 PDE10A (0.44) PDE10AKDM4EGPR3ALDH1A1HPGD
Ethane SCHEMBL27894198 0.77 PDE10A (0.44) PDE10AKDM4EGPR3ALDH1A1HPGD
SCHEMBL5720367 0.74 PDE10A (0.48) PDE10AKDM4EGPR3ALDH1A1HPGD
SCHEMBL29396869 0.73 KDM4E (0.41) PDE10AKDM4EGPR3ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117466826-A Preparation method of 2, 3-fluoroalkyl quinoxaline compound 昆明理工大学 2024-01-30 CN disclosed