SCHEMBL29185283

SCHEMBL29185283

COCCOCCCc1cc(NC2CCOCC2)c2[nH]c(-c3ccccc3)cc2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 7/20 0.39
CARM1 Q86X55 2/20 0.36
NPY5R Q15761 4/20 0.33
KIT P10721 1/20 0.32
FLT3 P36888 1/20 0.32
MAPK1 P28482 1/20 0.32
CD38 P28907 1/20 0.32
TUBB4A P04350 1/20 0.32
TUBB P07437 1/20 0.32
TUBA3C P0DPH7 1/20 0.32
TUBA1B P68363 1/20 0.32
TUBA4A P68366 1/20 0.32
TUBB4B P68371 1/20 0.32
TUBB3 Q13509 1/20 0.32
TUBB2A Q13885 1/20 0.32
TUBB8 Q3ZCM7 1/20 0.32
TUBA3E Q6PEY2 1/20 0.32
TUBA1A Q71U36 1/20 0.32
TUBA1C Q9BQE3 1/20 0.32
TUBB6 Q9BUF5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30224123 1.00 CSF1R (0.39) CSF1RCARM1NPY5RKITFLT3
SCHEMBL30224118 0.95 CSF1R (0.40) CSF1RCARM1NPY5RKITFLT3
SCHEMBL27237594 0.95 CSF1R (0.40) CSF1RCARM1NPY5RKITFLT3
SCHEMBL29205665 0.95 CSF1R (0.41) CSF1RCARM1NPY5RMAPK1TUBB4A
SCHEMBL30182996 0.95 CSF1R (0.41) CSF1RCARM1NPY5RMAPK1TUBB4A
SCHEMBL30224873 0.92 CSF1R (0.40) CSF1RCARM1NPY5RKITFLT3
SCHEMBL27237572 0.92 CSF1R (0.40) CSF1RCARM1NPY5RKITFLT3
SCHEMBL25015330 0.92 CSF1R (0.42) CSF1RCARM1NPY5RMAPK1TUBB4A
SCHEMBL29205646 0.91 NPY5R (0.41) CSF1RCARM1NPY5RTUBB4ATUBB
SCHEMBL30224759 0.91 CSF1R (0.40) CSF1RCARM1NPY5RKITFLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117794917-A Novel indole derivatives, pharmaceutical compositions containing the same and uses thereof 水疗免疫疗法有限公司 2024-03-29 CN claimed
CN-117794917-A Novel indole derivatives, pharmaceutical compositions containing the same and uses thereof 水疗免疫疗法有限公司 2024-03-29 CN disclosed