SCHEMBL2918704

SCHEMBL2918704

C[Si](O)(O[Si](C)(O[Si](C)(O)c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 2/20 0.40
NR1H3 Q13133 2/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
MAPT P10636 1/20 0.32
NR1I2 O75469 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4619514 0.98 NR1H2 (0.39) NR1H2NR1H3ESR1ESR2CES2
SCHEMBL10486795 0.98 NR1H2 (0.39) NR1H2NR1H3ESR1ESR2CES2
SCHEMBL2919598 0.88 ESR1 (0.44) NR1H2NR1H3ESR1ESR2CES2
SCHEMBL12160321 0.84 ESR1 (0.41) NR1H2NR1H3ESR1ESR2CES2
SCHEMBL12979079 0.84 ESR1 (0.41) NR1H2NR1H3ESR1ESR2CES2
SCHEMBL12979782 0.84 ESR1 (0.41) NR1H2NR1H3ESR1ESR2CES2
SCHEMBL14418535 0.84 ESR1 (0.41) NR1H2NR1H3ESR1ESR2CES2
SCHEMBL10387746 0.82 NR1H2 (0.40) NR1H2NR1H3ESR1ESR2CES2
SCHEMBL15800382 0.82 NR1H2 (0.40) NR1H2NR1H3ESR1ESR2CES2
SCHEMBL18692028 0.78 NR1H2 (0.38) NR1H2NR1H3ESR1ESR2CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3133105-B1 HYDROSILYL-CONTAINING ORGANOPOLYSILOXANE, MAKING METHOD, ADDITION CURABLE SILICONE COMPOSITION, AND SEMICONDUCTOR PACKAGE SHINETSU CHEMICAL CO (JP) 2020-12-09 EP disclosed
US-9994711-B2 Condensation-curable silicone composition and a semiconductor device SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-06-12 US disclosed
US-9890251-B2 Hydrosilyl-containing organopolysiloxane, making method, addition curable silicone composition, and semiconductor package SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-02-13 US disclosed
US-9862803-B2 Branched organopolysiloxane and a method for preparing the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-01-09 US disclosed
US-9587075-B2 Addition-curable silicone composition and a semiconductor device SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-03-07 US disclosed
EP-3133105-A1 HYDROSILYL-CONTAINING ORGANOPOLYSILOXANE, MAKING METHOD, ADDITION CURABLE SILICONE COMPOSITION, AND SEMICONDUCTOR PACKAGE Shin-Etsu Chemical Co., Ltd. (JP) 2017-02-22 EP disclosed
US-20170029571-A1 HYDROSILYL-CONTAINING ORGANOPOLYSILOXANE, MAKING METHOD, ADDITION CURABLE SILICONE COMPOSITION, AND SEMICONDUCTOR PACKAGE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-02-02 US disclosed
US-20160304675-A1 BRANCHED ORGANOPOLYSILOXANE AND A METHOD FOR PREPARING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-10-20 US disclosed
US-20160304673-A1 ADDITION-CURABLE SILICONE COMPOSITION AND A SEMICONDUCTOR DEVICE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-10-20 US disclosed
US-20160280959-A1 CONDENSATION-CURABLE SILICONE COMPOSITION AND A SEMICONDUCTOR DEVICE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-09-29 US disclosed
EP-1334975-B1 Silylation of hydroxyl group-containing compounds SHINETSU CHEMICAL CO (JP) 2006-07-12 EP disclosed
US-6924008-B2 Curable resin composition, a method for the preparation thereof, and a coated article thereof DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2005-08-02 US disclosed
US-6875880-B2 Silylation of hydroxyl groups SHIN-ETSU CHEMICAL, CO., LTD. (JP) 2005-04-05 US disclosed
EP-1334975-A1 Silylation of hydroxyl group-containing compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-08-13 EP disclosed
US-20030139619-A1 Silylation of hydroxyl groups SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-07-24 US disclosed
US-20030032729-A1 Curable resin composition, process for producing the same, and coated object made with the same DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-02-13 US disclosed
US-6437090-B1 ORGANOMETALLIC COMPOUND CAPABLE OF REVERSIBLY DISSOLVING AND PRECIPITATING THROUGH HEATING AND COOLING; ORGANOSILICON COMPOUND; ONE LIGAND CONTAINS AN ALKYL GROUP HAVING 10 OR MORE CARBON ATOMS; EPOXY RESIN; STORAGE STABLE; ONLY CURES ON HEAT KABUSHIKI KAISHA TOSHIBA (JP) 2002-08-20 US disclosed
EP-1172393-A1 CURABLE RESIN COMPOSITION, PROCESS FOR PRODUCING THE SAME, AND COATED OBJECT MADE WITH THE SAME DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2002-01-16 EP disclosed
US-6096836-A OXYGEN CONTAINING AROMATIC CATALYST AND ALUMINUM COMPOUND KABUSHIKI KAISHA TOSHIBA (JP) 2000-08-01 US disclosed
US-5811497-A STORAGE STABLE EPOXY RESINS ACTIVATE THE CURING WHEN APPLYING THE HEAT; FLEXIBILITY, DIELECTRIC, MECHANICAL STRENGTH KABUSHIKI KAISHA TOSHIBA (JP) 1998-09-22 US disclosed