Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14627937 | 1.00 | CHRM2 (0.38) | CHRM2CHRM1CYP2D6KMT2AMEN1 | |
| SCHEMBL29189672 | 1.00 | CHRM2 (0.38) | CHRM2CHRM1CYP2D6KMT2AMEN1 | |
| SCHEMBL24752585 | 1.00 | CHRM2 (0.38) | CHRM2CHRM1CYP2D6KMT2AMEN1 | |
| SCHEMBL10440862 | 0.88 | CHRM2 (0.42) | CHRM2CHRM1CYP2D6KMT2AMEN1 | |
| SCHEMBL19082714 | 0.84 | CHRM2 (0.38) | CHRM2CHRM1CYP2D6KMT2AMEN1 | |
| SCHEMBL24752327 | 0.84 | CHRM2 (0.38) | CHRM2CHRM1CYP2D6KMT2AMEN1 | |
| SCHEMBL17294429 | 0.84 | CHRM2 (0.38) | CHRM2CHRM1CYP2D6KMT2AMEN1 | |
| SCHEMBL24792569 | 0.84 | CHRM2 (0.38) | CHRM2CHRM1CYP2D6KMT2AMEN1 | |
| SCHEMBL24145355 | 0.82 | POLB (0.38) | CHRM2CHRM1CYP2D6KMT2AMEN1 | |
| SCHEMBL17928956 | 0.82 | POLB (0.38) | CHRM2CHRM1CYP2D6KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881681-A | Substituted pyrrolo [2,3-d ] pyrimidines, their preparation and their therapeutic use | 赛诺菲 | 2024-04-12 | — | — | CN | disclosed |