Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 14/20 | 0.67 |
| ▸ | FLT3 | P36888 | 2/20 | 0.60 |
| ▸ | MET | P08581 | 2/20 | 0.58 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.55 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190642 | 0.92 | ALK (0.59) | ALKFLT3METGLO1EGFR | |
| SCHEMBL29190699 | 0.92 | ALK (0.66) | ALKFLT3METGLO1PTK2 | |
| SCHEMBL29190714 | 0.88 | ALK (0.61) | ALKFLT3METGLO1EGFR | |
| SCHEMBL29190632 | 0.86 | ALK (0.63) | ALKFLT3METGLO1PTK2 | |
| SCHEMBL29190563 | 0.85 | ALK (0.64) | ALKFLT3METGLO1PTK2 | |
| SCHEMBL29190605 | 0.85 | ALK (0.67) | ALKFLT3METEGFR | |
| SCHEMBL29190607 | 0.83 | ALK (0.63) | ALKFLT3METGLO1PTK2 | |
| SCHEMBL30833625 | 0.83 | ALK (0.52) | ALKFLT3 | |
| SCHEMBL29190707 | 0.83 | ALK (0.52) | ALKFLT3 | |
| SCHEMBL29190590 | 0.82 | ALK (0.70) | ALKFLT3METGLO1PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |