Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK7 | Q13164 | 12/20 | 0.55 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.50 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 4/20 | 0.45 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | GAK | O14976 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648198 | 0.87 | MAPK7 (0.56) | MAPK7PDE1BIRAK4EGFRACHE | |
| SCHEMBL3563598 | 0.84 | MAPK7 (0.54) | MAPK7PDE1BIRAK4EGFRKDR | |
| SCHEMBL29190833 | 0.84 | MAPK7 (0.54) | MAPK7PDE1BIRAK4EGFRSRC | |
| Hydrochloric Acid SCHEMBL29055053 | 0.83 | MAPK7 (0.53) | MAPK7PDE1BIRAK4EGFRKDR | |
| SCHEMBL20813639 | 0.81 | MAPK7 (0.54) | MAPK7PDE1BACHEBACE1 | |
| SCHEMBL20798135 | 0.81 | MAPK7 (0.51) | MAPK7PDE1BKDRACHEBACE1 | |
| SCHEMBL20797981 | 0.79 | MAPK7 (0.52) | MAPK7PDE1BACHEBACE1 | |
| SCHEMBL30776980 | 0.79 | MAPK7 (0.52) | MAPK7PDE1BACHEBACE1 | |
| SCHEMBL27112047 | 0.79 | MAPK7 (0.49) | MAPK7PDE1BKDR | |
| SCHEMBL4962360 | 0.78 | MAPK7 (0.71) | MAPK7ACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117883449-A | ENPP1 inhibitors and their use for the treatment of cancer | 里兰斯坦福初级大学理事会 | 2024-04-16 | — | — | CN | disclosed |
| CN-111372587-B | ENPP1 inhibitors and their use for the treatment of cancer | 里兰斯坦福初级大学理事会 | 2024-01-09 | — | — | CN | disclosed |