Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29191049 | 0.86 | KMT2A (0.54) | KMT2AKDM4EMEN1MAPTALDH1A1 | |
| SCHEMBL29190981 | 0.86 | F2 (0.56) | KMT2AKDM4EMEN1TDP1MAPT | |
| SCHEMBL29191034 | 0.86 | KMT2A (0.54) | KMT2AKDM4EMEN1MAPTALDH1A1 | |
| SCHEMBL29191053 | 0.84 | KMT2A (0.56) | KMT2AKDM4EMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29190973 | 0.82 | CYP11B1 (0.44) | KDM4EMAPTALDH1A1PKMNPC1 | |
| SCHEMBL29191002 | 0.81 | POLB (0.51) | KMT2AKDM4EMEN1TDP1MAPT | |
| SCHEMBL29191097 | 0.80 | KMT2A (0.43) | KMT2AMEN1MAPTALDH1A1PKM | |
| SCHEMBL30874561 | 0.80 | KMT2A (0.43) | KMT2AMEN1MAPTALDH1A1PKM | |
| SCHEMBL29191057 | 0.77 | ELANE (0.44) | KMT2AKDM4EMAPTALDH1A1NPC1 | |
| SCHEMBL29191039 | 0.77 | MAPT (0.47) | KMT2AKDM4EMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117886734-A | Heterocyclic amide compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-04-16 | — | — | CN | disclosed |