Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.30 |
| ▸ | LSS | P48449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29194901 | 1.00 | ADORA2A (0.40) | ADORA2AADORA2BGRM4QPCTLSS | |
| SCHEMBL30031152 | 1.00 | ADORA2A (0.40) | ADORA2AADORA2BGRM4QPCTLSS | |
| SCHEMBL24758367 | 1.00 | ADORA2A (0.40) | ADORA2AADORA2BGRM4QPCTLSS | |
| SCHEMBL30032578 | 0.90 | ADORA2A (0.40) | ADORA2AADORA2BGRM4QPCTLSS | |
| SCHEMBL29194818 | 0.90 | ADORA2A (0.40) | ADORA2AADORA2BGRM4QPCTLSS | |
| SCHEMBL29194817 | 0.90 | ADORA2A (0.40) | ADORA2AADORA2BGRM4QPCTLSS | |
| SCHEMBL29194821 | 0.90 | ADORA2A (0.40) | ADORA2AADORA2BGRM4QPCTLSS | |
| SCHEMBL30200710 | 0.84 | KDM4E (0.31) | GRM4 | |
| SCHEMBL26648133 | 0.84 | KDM4E (0.31) | GRM4 | |
| SCHEMBL26648804 | 0.84 | KDM4E (0.31) | GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4401729-A1 | BCL-XL DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-07-24 | — | — | EP | disclosed |
| CN-117916239-A | 3-Substituted 1H-pyrrolo [2,3-b ] pyridines as GRK5 modulators | 利德探索中心股份有限公司 | 2024-04-19 | — | — | CN | disclosed |
| WO-2023044046-A1 | BCL-XL DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-03-23 | — | — | WO | disclosed |