Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 19/20 | 0.69 |
| ▸ | CRBN | Q96SW2 | 19/20 | 0.69 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30663024 | 0.94 | DDB1 (0.70) | DDB1CRBNPDE4B | |
| SCHEMBL30662925 | 0.94 | DDB1 (0.70) | DDB1CRBNPDE4B | |
| SCHEMBL30663164 | 0.93 | DDB1 (0.67) | DDB1CRBNPDE4B | |
| SCHEMBL30662917 | 0.93 | DDB1 (0.67) | DDB1CRBNPDE4B | |
| SCHEMBL23540247 | 0.92 | DDB1 (0.75) | DDB1CRBN | |
| SCHEMBL30026749 | 0.92 | DDB1 (0.75) | DDB1CRBN | |
| SCHEMBL34461219 | 0.88 | DDB1 (0.70) | DDB1CRBN | |
| SCHEMBL31323556 | 0.88 | DDB1 (0.68) | DDB1CRBN | |
| SCHEMBL34461272 | 0.88 | DDB1 (0.68) | DDB1CRBN | |
| SCHEMBL26501787 | 0.88 | DDB1 (0.70) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940133-A | Therapeutic agents for degradation of mutant BRAF | C4医药公司 | 2024-04-26 | — | — | CN | disclosed |
| EP-4351583-A1 | THERAPEUTICS FOR THE DEGRADATION OF MUTANT BRAF | C4 Therapeutics, Inc. (US) | 2024-04-17 | — | — | EP | disclosed |
| WO-2022261250-A1 | THERAPEUTICS FOR THE DEGRADATION OF MUTANT BRAF | C4 THERAPEUTICS, INC. (US) | 2022-12-15 | — | — | WO | disclosed |