Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL29198540

O=C(O)C(F)(F)F.O=C1CCN(c2ccc(N3CCN(C4CCNCC4)CC3)cc2)C(=O)N1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 4/20 0.44
CRBN Q96SW2 4/20 0.44
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
KHK P50053 4/20 0.37
GRIN2B Q13224 1/20 0.36
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 1/20 0.36
MAPT P10636 1/20 0.35
HIF1A Q16665 1/20 0.35
ITGB3 P05106 1/20 0.35
ITGA2B P08514 1/20 0.35
MMP2 P08253 1/20 0.35
MMP13 P45452 1/20 0.35
SLC18A3 Q16572 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24678276 0.90 DDB1 (0.52) DDB1CRBNMEN1KMT2AKHK
Trifluoroacetic Acid SCHEMBL30525353 0.89 DDB1 (0.46) DDB1CRBNMEN1KMT2AKHK
Hydrochloric Acid SCHEMBL30525354 0.89 DDB1 (0.51) DDB1CRBNMEN1KMT2AKHK
Trifluoroacetic Acid SCHEMBL31230624 0.88 DDB1 (0.41) DDB1CRBNMEN1KMT2AKDM4E
SCHEMBL25222977 0.88 DDB1 (0.50) DDB1CRBNMEN1KMT2AKHK
Hydrochloric Acid SCHEMBL31230691 0.87 DDB1 (0.49) DDB1CRBNMEN1KMT2AKHK
Trifluoroacetic Acid SCHEMBL31630892 0.86 DDB1 (0.52) DDB1CRBNKDM4EALDH1A1HPGD
SCHEMBL25631809 0.85 DDB1 (0.48) DDB1CRBNMEN1KMT2AKHK
Trifluoroacetic Acid SCHEMBL29198403 0.85 CRBN (0.41) DDB1CRBNKDM4EALDH1A1HPGD
Hydrochloric Acid SCHEMBL31230703 0.84 DDB1 (0.47) DDB1CRBNMEN1KMT2AKHK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117425646-A Phosphono derivative, composition thereof and pharmaceutical application thereof 西藏海思科制药有限公司 2024-01-19 CN disclosed