SCHEMBL29198968

SCHEMBL29198968

CNC(=O)OC1CCN(Cc2cc(Oc3ccc(N4CCNCC4)nc3)nc(-c3cc(Cl)cc(Cl)c3)c2)CC1

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25180653 0.93 FURIN (0.64) FURIN
SCHEMBL29199009 0.91 FURIN (0.74) FURIN
SCHEMBL21551591 0.90 FURIN (0.64) FURIN
SCHEMBL29928863 0.90 FURIN (0.64) FURIN
SCHEMBL25180652 0.90 FURIN (0.63) FURIN
SCHEMBL30387870 0.90 FURIN (0.63) FURIN
SCHEMBL29199005 0.88 FURIN (0.62) FURIN
SCHEMBL21551251 0.88 FURIN (0.70) FURIN
SCHEMBL21550928 0.87 FURIN (0.81) FURIN
SCHEMBL21550819 0.87 FURIN (0.82) FURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112384509-B Furin inhibitors 葛兰素史密斯克莱知识产权发展有限公司 2024-04-30 — — CN disclosed
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