Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 9/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP1 | P63208 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21564572 | 1.00 | FURIN (0.54) | FURINCHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL29890932 | 1.00 | FURIN (0.54) | FURINCHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL29199011 | 1.00 | FURIN (0.54) | FURINCHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL21551399 | 0.92 | FURIN (0.59) | FURINCHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL21551397 | 0.92 | FURIN (0.59) | FURINCHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL21551401 | 0.92 | FURIN (0.59) | FURINCHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL26077365 | 0.89 | FURIN (0.60) | FURINCHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL24872438 | 0.87 | FURIN (0.59) | FURINCHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL21551019 | 0.87 | FURIN (0.59) | FURINCHRM2CHRM1CHRM4CHRM5 | |
| SCHEMBL21551021 | 0.87 | FURIN (0.59) | FURINCHRM2CHRM1CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384509-B | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-04-30 | — | — | CN | disclosed |