Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 19/20 | 0.76 |
| ▸ | LCK | P06239 | 17/20 | 0.76 |
| ▸ | EGFR | P00533 | 7/20 | 0.76 |
| ▸ | BTK | Q06187 | 13/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29199692 | 1.00 | JAK3 (0.76) | JAK3LCKEGFRBTK | |
| SCHEMBL29264631 | 0.93 | JAK3 (0.66) | JAK3LCKEGFRBTK | |
| SCHEMBL16763889 | 0.86 | JAK3 (1.00) | JAK3LCKEGFRBTK | |
| SCHEMBL29871796 | 0.86 | JAK3 (1.00) | JAK3LCKEGFRBTK | |
| SCHEMBL16763891 | 0.86 | JAK3 (1.00) | JAK3LCKEGFRBTK | |
| SCHEMBL29264612 | 0.86 | JAK3 (0.56) | JAK3LCKEGFRBTK | |
| SCHEMBL24833610 | 0.85 | JAK3 (0.87) | JAK3LCKEGFRBTK | |
| SCHEMBL28653352 | 0.85 | JAK3 (0.85) | JAK3LCKEGFRBTK | |
| SCHEMBL21855226 | 0.84 | JAK3 (0.79) | JAK3LCKEGFRBTK | |
| SCHEMBL24832883 | 0.84 | JAK3 (0.82) | JAK3LCKEGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916231-A | Compounds for inhibiting or degrading target proteins, compositions comprising the same, methods of making and methods of using the same | 纽力克斯治疗公司 | 2024-04-19 | — | — | CN | disclosed |