SCHEMBL29199840

SCHEMBL29199840

Cc1ccc(F)c([C@H](C)N[S+]([O-])C(C)(C)C)c1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.31
POLB P06746 1/20 0.31
HTR2A P28223 1/20 0.31
SLC6A4 P31645 1/20 0.31
KCNH2 Q12809 1/20 0.31
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29199841 1.00 CNR1 (0.31) CNR1POLBHTR2ASLC6A4KCNH2
SCHEMBL26345777 1.00 CNR1 (0.31) CNR1POLBHTR2ASLC6A4KCNH2
SCHEMBL20237851 0.86 PSEN1 (0.40) HTR2ASLC6A4KCNH2
SCHEMBL29668771 0.86 PSEN1 (0.40) HTR2ASLC6A4KCNH2
SCHEMBL30582950 0.86 PSEN1 (0.40) HTR2ASLC6A4KCNH2
SCHEMBL23148371 0.86 PSEN1 (0.40) HTR2ASLC6A4KCNH2
SCHEMBL20237852 0.86 PSEN1 (0.40) HTR2ASLC6A4KCNH2
SCHEMBL23148369 0.86 PSEN1 (0.40) HTR2ASLC6A4KCNH2
SCHEMBL21063771 0.86 PSEN1 (0.40) HTR2ASLC6A4KCNH2
SCHEMBL20237848 0.86 PSEN1 (0.40) HTR2ASLC6A4KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117088854-A Pharmaceutically acceptable salts and crystal forms of triazinedione derivatives and preparation method thereof 江苏恒瑞医药股份有限公司 2023-11-21 CN disclosed
CN-116323598-A Triazine diketone derivative, preparation method and medical application thereof 江苏恒瑞医药股份有限公司 2023-06-23 CN disclosed