Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.85 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.62 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.51 |
| ▸ | PPIA | P62937 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30802625 | 1.00 | PARP1 (0.85) | PARP1PARP2SGMS2RXFP1LRRK2 | |
| SCHEMBL29200340 | 0.92 | PARP1 (1.00) | PARP1PARP2SGMS2LRRK2PPIA | |
| SCHEMBL30802616 | 0.92 | PARP1 (1.00) | PARP1PARP2SGMS2LRRK2PPIA | |
| SCHEMBL29200362 | 0.88 | PARP1 (0.66) | PARP1PARP2SGMS2RXFP1PPIA | |
| SCHEMBL29200328 | 0.87 | PARP1 (0.65) | PARP1PARP2SGMS2LRRK2PPIA | |
| SCHEMBL30802647 | 0.87 | PPIA (0.65) | PARP1PARP2SGMS2LRRK2PPIA | |
| SCHEMBL30802654 | 0.87 | PARP1 (0.65) | PARP1PARP2SGMS2LRRK2PPIA | |
| SCHEMBL29200330 | 0.87 | PARP1 (0.65) | PARP1PARP2SGMS2LRRK2PPIA | |
| SCHEMBL29200344 | 0.87 | PPIA (0.65) | PARP1PARP2SGMS2LRRK2PPIA | |
| SCHEMBL30802630 | 0.87 | PARP1 (0.65) | PARP1PARP2SGMS2LRRK2PPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | claimed |
| CN-117658868-A | Benzamide derivative and preparation method and application thereof | 中山大学 | 2024-03-08 | — | — | CN | disclosed |