⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL21591806 | 0.69 | — | — | |
| SCHEMBL10764211 | 0.67 | — | — | |
| SCHEMBL555067 | 0.67 | — | — | |
| SCHEMBL28369351 | 0.67 | — | — | |
| SCHEMBL132008 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL29148029 | 0.64 | — | — | |
| SCHEMBL132007 | 0.64 | — | — | |
| SCHEMBL14098372 | 0.62 | — | — | |
| SCHEMBL2918378 | 0.62 | — | — | |
| SCHEMBL2919918 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112552312-A | Synthetic method of Ruogeli or salt thereof | 杭州科巢生物科技有限公司 | 2021-03-26 | — | — | CN | claimed |
| US-20070060558-A1 | Hybrid molecules QA where Q is an aminoquinoline and A is an antibiotic residue, the synthesis and uses thereof as antibacterial agents | PALUMED S.A. (FR) | 2007-03-15 | — | — | US | claimed |
| US-11447445-B2 | Diabetes and metabolic syndrome treatment with a novel dual modulator of soluble epoxide hydrolase and peroxisome proliferator-activated receptors | THE MEDICAL COLLEGE OF WISCONSIN, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| CN-112552312-B | Synthetic method of Ruogeli or salt thereof | 杭州科巢生物科技有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-112552312-A | Synthetic method of Ruogeli or salt thereof | 杭州科巢生物科技有限公司 | 2021-03-26 | — | — | CN | disclosed |
| US-20140030784-A1 | Terpene Synthases and Methods of Using the Same | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2014-01-30 | — | — | US | disclosed |
| EP-1591443-B1 | PYRAZOLE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2010-08-25 | — | — | EP | disclosed |
| US-7622471-B2 | Pyrazole derivatives having a pyridazine and pyridine functionality | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-11-24 | — | — | US | disclosed |
| CN-101035769-A | Pyrimidine urea derivatives as kinase inhibitors | NOVARTIS AG (CH) | 2007-09-12 | — | — | CN | disclosed |
| US-20070060558-A1 | Hybrid molecules QA where Q is an aminoquinoline and A is an antibiotic residue, the synthesis and uses thereof as antibacterial agents | PALUMED S.A. (FR) | 2007-03-15 | — | — | US | disclosed |
| US-20060128685-A1 | Pyrazole derivative | DAIICHI PHARMACEUTICAL CO., LTD., (JP) | 2006-06-15 | — | — | US | disclosed |
| EP-1591443-A1 | PYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004014425-A1 | ACTIVATORS OF SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNELS AND USE THEREOF | GLAXO GROUP LIMITED (GB) | 2004-02-19 | — | — | WO | disclosed |
| EP-0763043-A1 | PROCESS FOR THE PREPARATION OF TRIHYDRATED CEFIXIME | MARCHAM TRADING & INVESTMENT LTD. (IE) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033753-A1 | PROCESS FOR THE PREPARATION OF TRIHYDRATED CEFIXIME | MARCHAM TRADING & INVESTMENT LTD. (IE) | 1995-12-14 | — | — | WO | disclosed |
| US-5200403-A | Inhibition of βlactamase with 6 β-(substituted methyl)-penicillanic acid derivatives | FARMITALIA CARLO ERBA S.R.L. (IT) | 1993-04-06 | — | — | US | disclosed |