Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15068967 | 0.85 | DDB1 (0.47) | PRKCIMAPTKDM4EALDH1A1DDB1 | |
| SCHEMBL3655093 | 0.81 | PRKCI (0.41) | PRKCIMAPTKDM4EALDH1A1DDB1 | |
| SCHEMBL29992674 | 0.79 | ADORA2A (0.59) | PRKCIMAPTKDM4EALDH1A1DDB1 | |
| SCHEMBL3376205 | 0.79 | ADORA2A (0.59) | PRKCIMAPTKDM4EALDH1A1DDB1 | |
| SCHEMBL21430231 | 0.79 | ADORA2A (0.39) | MAPTKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL29200977 | 0.78 | PRKCI (0.39) | PRKCIMAPTKDM4EALDH1A1DDB1 | |
| SCHEMBL30410816 | 0.78 | PRKCI (0.39) | PRKCIMAPTKDM4EALDH1A1DDB1 | |
| SCHEMBL10075621 | 0.78 | PRKCI (0.39) | PRKCIMAPTKDM4EALDH1A1DDB1 | |
| SCHEMBL30896811 | 0.76 | DDB1 (0.46) | PRKCIMAPTKDM4EALDH1A1DDB1 | |
| Hydrochloric Acid SCHEMBL21409087 | 0.76 | CSNK2A1 (0.36) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332950-A | Indazole substituted podophyllotoxin derivative and preparation method and application thereof | 汤亚杰 | 2023-06-27 | — | — | CN | claimed |
| CN-116332950-A | Indazole substituted podophyllotoxin derivative and preparation method and application thereof | 汤亚杰 | 2023-06-27 | — | — | CN | disclosed |