Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 12/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30880825 | 1.00 | CNR1 (0.52) | CNR1ALDH1A1ADORA2AADORA2BADORA1 | |
| SCHEMBL30712635 | 0.90 | CNR1 (0.61) | CNR1ALDH1A1 | |
| SCHEMBL2830367 | 0.90 | CNR1 (0.61) | CNR1ALDH1A1 | |
| SCHEMBL28961575 | 0.89 | CNR1 (0.49) | CNR1ALDH1A1ADORA2AADORA2BADORA1 | |
| SCHEMBL3999845 | 0.86 | CNR1 (0.66) | CNR1 | |
| SCHEMBL4816393 | 0.80 | CNR1 (0.68) | CNR1 | |
| SCHEMBL29907688 | 0.77 | ADORA2A (0.52) | ALDH1A1ADORA2AADORA2BADORA1KDM4E | |
| SCHEMBL22551869 | 0.77 | ADORA2A (0.52) | ALDH1A1ADORA2AADORA2BADORA1KDM4E | |
| SCHEMBL9695575 | 0.76 | CNR1 (0.66) | CNR1ALDH1A1KDM4EMAPTPKM | |
| SCHEMBL2834588 | 0.74 | CNR1 (0.62) | CNR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115181092-B | Pyrazine compounds and uses thereof | 迪哲(江苏)医药股份有限公司 | 2024-05-03 | — | — | CN | disclosed |