SCHEMBL29201466

SCHEMBL29201466

N#CCCC#Cc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.52
CYP2C9 P11712 2/20 0.52
CYP2C19 P33261 2/20 0.52
CYP1A2 P05177 1/20 0.52
THPO P40225 1/20 0.52
BLM P54132 1/20 0.50
PMP22 Q01453 1/20 0.50
TSHR P16473 2/20 0.49
APP P05067 1/20 0.48
HRH3 Q9Y5N1 1/20 0.47
HTR2A P28223 1/20 0.44
NPSR1 Q6W5P4 1/20 0.42
LMNA P02545 1/20 0.41
HTT P42858 1/20 0.41
HAO1 Q9UJM8 1/20 0.41
FFAR1 O14842 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40
SIGMAR1 Q99720 1/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10768214 0.88 CYP1A2 (0.64) CYP3A4CYP2C9CYP2C19CYP1A2THPO
SCHEMBL29118813 0.87 CYP3A4 (0.48) CYP3A4CYP2C9CYP2C19CYP1A2THPO
SCHEMBL21924472 0.79 CYP3A4 (0.54) CYP3A4CYP2C9CYP2C19CYP1A2THPO
SCHEMBL28117897 0.79 CYP1A2 (0.54) CYP3A4CYP2C9CYP2C19CYP1A2THPO
SCHEMBL17911731 0.78 CYP1A2 (0.58) CYP3A4CYP2C9CYP2C19CYP1A2THPO
SCHEMBL10455227 0.77 CYP1A2 (0.52) CYP3A4CYP2C9CYP2C19CYP1A2THPO
SCHEMBL28454184 0.75 CYP3A4 (0.45) CYP3A4CYP2C9CYP2C19CYP1A2THPO
SCHEMBL9784179 0.74 CYP1A2 (0.54) CYP3A4CYP2C9CYP2C19CYP1A2THPO
SCHEMBL5808117 0.74 CYP1A2 (0.54) CYP3A4CYP2C9CYP2C19CYP1A2THPO
SCHEMBL613220 0.74 CYP1A2 (0.54) CYP3A4CYP2C9CYP2C19CYP1A2THPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115724769-B Method for synthesizing fluorine-containing phenylethynyl phenyl propionitrile liquid crystal compound 西安瑞联新材料股份有限公司 2024-05-03 CN disclosed