Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dl-Phenylalanine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | CTSC | P53634 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.33 |
| ▸ | TPH1 | P17752 | 2/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL3490081 | 0.93 | CYP3A4 (0.32) | SLC7A5CTSC | |
| Histidine SCHEMBL790244 | 0.93 | CYP3A4 (0.32) | SLC7A5CTSC | |
| Histidine SCHEMBL3088582 | 0.93 | CYP3A4 (0.32) | SLC7A5CTSC | |
| Histidine SCHEMBL790243 | 0.93 | CYP3A4 (0.32) | SLC7A5CTSC | |
| Histidine SCHEMBL1675273 | 0.93 | CYP3A4 (0.32) | SLC7A5CTSC | |
| Phenylalanine SCHEMBL8810515 | 0.90 | ALPI (0.38) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Histidine SCHEMBL18280908 | 0.89 | CYP3A4 (0.30) | SLC7A5CTSC | |
| Histidine SCHEMBL2586200 | 0.89 | SLC7A5 (0.35) | ALPIPKMPTGS1XIAPSLC7A5 | |
| D-Histidine SCHEMBL11606906 | 0.89 | SLC7A5 (0.35) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Histidine SCHEMBL27902238 | 0.89 | SLC7A5 (0.35) | ALPIPKMPTGS1XIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116813699-B | Ovalbumin anti-inflammatory peptide and application thereof | 杭州佰倍优生物科技有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-116813699-A | Ovalbumin anti-inflammatory peptide and application thereof | 杭州佰倍优生物科技有限公司 | 2023-09-29 | — | — | CN | disclosed |