⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1264729 | 0.92 | CRBN (0.53) | — | |
| SCHEMBL9110121 | 0.89 | CRBN (0.50) | — | |
| SCHEMBL5960403 | 0.89 | CRBN (0.50) | — | |
| SCHEMBL11802065 | 0.89 | CRBN (0.50) | — | |
| SCHEMBL3999349 | 0.87 | CXCR4 (0.53) | — | |
| SCHEMBL8217380 | 0.85 | CXCR4 (0.50) | — | |
| Cyclohexane SCHEMBL6276395 | 0.85 | CRBN (0.41) | — | |
| SCHEMBL21785045 | 0.84 | CRBN (0.47) | — | |
| SCHEMBL9058472 | 0.84 | CRBN (0.47) | — | |
| SCHEMBL31059 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090104116-A1 | COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF | JERINI AG (DE) | 2009-04-23 | — | — | US | claimed |
| EP-1979342-A1 | COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF | Jerini AG (DE) | 2008-10-15 | — | — | EP | claimed |
| WO-2007088041-A1 | COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF | JERINI AG (DE) | 2007-08-09 | — | — | WO | claimed |
| EP-3212705-B1 | OXALIC ACID DIAMIDES AS MODIFIERS FOR POLYOLEFIN CATALYSTS | FORMOSA PLASTICS CORP USA (US) | 2021-03-10 | — | — | EP | disclosed |
| US-10822438-B2 | Catalyst system for enhanced stereo-specificity of olefin polymerization and method for producing olefin polymer | FORMOSA PLASTICS CORPORATION (US) | 2020-11-03 | — | — | US | disclosed |
| US-9777084-B2 | Catalyst system for olefin polymerization and method for producing olefin polymer | FORMOSA PLASTICS CORPORATION, USA (US) | 2017-10-03 | — | — | US | disclosed |
| US-20170240667-A1 | Catalyst System for Olefin Polymerization and Method for Producing Olefin Polymer | FORMOSA PLASTICS CORPORATION, USA | 2017-08-24 | — | — | US | disclosed |
| US-9593184-B2 | Oxalic acid diamides as modifiers for polyolefin catalysts | FORMOSA PLASTICS CORPORATION, USA (US) | 2017-03-14 | — | — | US | disclosed |
| US-20160115260-A1 | Oxalic Acid Diamides As Modifiers For Polyolefin Catalysts | FORMOSA PLASTICS CORPORATION, USA | 2016-04-28 | — | — | US | disclosed |
| US-8927534-B2 | Compounds for the inhibition of integrins and use thereof | SHIRE ORPHAN THERAPIES GMBH (DE) | 2015-01-06 | — | — | US | disclosed |
| EP-1591443-B1 | PYRAZOLE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2010-08-25 | — | — | EP | disclosed |
| EP-1785418-A1 | PYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-05-16 | — | — | EP | disclosed |
| EP-1762568-A1 | PYRAZOLE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-14 | — | — | EP | disclosed |
| US-20060189591-A1 | Five-membered heterocyclic derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-08-24 | — | — | US | disclosed |
| US-20060128685-A1 | Pyrazole derivative | DAIICHI PHARMACEUTICAL CO., LTD., (JP) | 2006-06-15 | — | — | US | disclosed |
| EP-1621537-A1 | FIVE-MEMBERED HETEROCYCLIC DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-02-01 | — | — | EP | disclosed |
| EP-1591443-A1 | PYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-11-02 | — | — | EP | disclosed |
| US-20050112693-A1 | Diketodiazacyclic compounds, diazacyclic compounds and combinatorial libraries thereof | NEFZI ADEL (US) | 2005-05-26 | — | — | US | disclosed |
| US-6809202-B2 | SYNTHETIC PEPTIDES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES | 2004-10-26 | — | — | US | disclosed |
| US-6441172-B1 | DI- AND TRI-SUBSTITUTED-1,4-DIAZACYCLIC COMPOUNDS | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES | 2002-08-27 | — | — | US | disclosed |