SCHEMBL29202249

SCHEMBL29202249

O=CONNCC1c2ccccc2-c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
KMT2A Q03164 2/20 0.35
FABP5 Q01469 3/20 0.35
FABP7 O15540 2/20 0.35
TSHR P16473 1/20 0.33
EPHX2 P34913 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
HDAC9 Q9UKV0 1/20 0.33
HDAC5 Q9UQL6 1/20 0.33
NCOR2 Q9Y618 1/20 0.33
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28617964 0.83 HTR2A (0.42) HTR2ACA1CA2KMT2AFABP5
SCHEMBL29202246 0.77 HTR2A (0.44) HTR2ACA1CA2KMT2ATSHR
SCHEMBL1509217 0.73 HTR2A (0.47) HTR2ACA1CA2KMT2ATSHR
SCHEMBL21896104 0.72 HTR2A (0.45) HTR2ACA1CA2KMT2ATSHR
SCHEMBL12719 0.69 CA1 (0.53) HTR2ACA1CA2KMT2AFABP5
SCHEMBL29393453 0.69 CA1 (0.53) HTR2ACA1CA2KMT2AFABP5
SCHEMBL28972124 0.69 KMT2A (0.43) HTR2ACA1CA2KMT2AFABP5
SCHEMBL31510343 0.67 CA1 (0.50) HTR2ACA1CA2KMT2AFABP5
SCHEMBL3087725 0.67 HTR2A (0.44) HTR2ACA1CA2KMT2AFABP5
SCHEMBL7270351 0.67 CA1 (0.50) HTR2ACA1CA2KMT2AFABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117964742-A Artificial metalloenzyme based on myoglobin scaffold, and chemical synthesis method and application thereof 华南理工大学 2024-05-03 CN claimed
CN-122011162-A Chemical synthesis method of N-terminal domain of TIMP2 protein 华南理工大学 2026-05-12 CN disclosed
CN-117964742-A Artificial metalloenzyme based on myoglobin scaffold, and chemical synthesis method and application thereof 华南理工大学 2024-05-03 CN disclosed