Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 16/20 | 0.72 |
| ▸ | ABL1 | P00519 | 16/20 | 0.72 |
| ▸ | PTK6 | Q13882 | 12/20 | 0.72 |
| ▸ | HCK | P08631 | 9/20 | 0.72 |
| ▸ | FYN | P06241 | 8/20 | 0.72 |
| ▸ | LYN | P07948 | 6/20 | 0.72 |
| ▸ | BLK | P51451 | 6/20 | 0.72 |
| ▸ | LCK | P06239 | 5/20 | 0.72 |
| ▸ | YES1 | P07947 | 5/20 | 0.72 |
| ▸ | FGR | P09769 | 5/20 | 0.72 |
| ▸ | FRK | P42685 | 6/20 | 0.68 |
| ▸ | KIT | P10721 | 1/20 | 0.68 |
| ▸ | RET | P07949 | 2/20 | 0.65 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.59 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.59 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.59 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.56 |
| ▸ | EGFR | P00533 | 3/20 | 0.56 |
| ▸ | KDR | P35968 | 3/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26134737 | 0.89 | ABL1 (0.61) | SRCABL1PTK6HCKFYN | |
| SCHEMBL20132684 | 0.88 | SRC (0.75) | SRCABL1PTK6HCKFYN | |
| SCHEMBL26148157 | 0.84 | ABL1 (0.83) | SRCABL1PTK6HCKFYN | |
| SCHEMBL20132619 | 0.84 | ABL1 (0.75) | SRCABL1PTK6HCKFYN | |
| SCHEMBL18258359 | 0.84 | SRC (1.00) | SRCABL1PTK6HCKFYN | |
| SCHEMBL29381545 | 0.84 | ABL1 (1.00) | SRCABL1PTK6HCKFYN | |
| SCHEMBL18258375 | 0.84 | ABL1 (1.00) | SRCABL1PTK6HCKFYN | |
| SCHEMBL18258357 | 0.84 | SRC (1.00) | SRCABL1PTK6HCKFYN | |
| SCHEMBL18258332 | 0.84 | SRC (1.00) | SRCABL1PTK6HCKFYN | |
| SCHEMBL18258328 | 0.83 | ABL1 (0.91) | SRCABL1PTK6HCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117957229-A | Tyrosine kinase inhibitors | 爱丁堡大学理事会 | 2024-04-30 | — | — | CN | disclosed |