Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | NMT2 | O60551 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | WNT1 | P04628 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30832028 | 1.00 | USP30 (0.38) | USP30RETNMT2NMT1FGFR4 | |
| Trifluoroacetic Acid SCHEMBL29208070 | 0.93 | HRH4 (0.38) | USP30RETITGB3ITGA2B | |
| SCHEMBL30832007 | 0.83 | HTR2A (0.38) | USP30ALDH1A1SMN1; SMN2HTR2A | |
| SCHEMBL30842106 | 0.79 | DEGS1 (0.40) | ALDH1A1SMN1; SMN2HTR2A | |
| SCHEMBL29208108 | 0.79 | HTR2A (0.40) | USP30ALDH1A1SMN1; SMN2HTR2A | |
| Trifluoroacetic Acid SCHEMBL29207944 | 0.78 | HTR2A (0.39) | USP30ITGB3ITGA2BHTR2A | |
| Trifluoroacetic Acid SCHEMBL29208063 | 0.74 | HTR2A (0.41) | ALDH1A1SMN1; SMN2HTR2A | |
| SCHEMBL29207966 | 0.74 | USP30 (0.42) | USP30ALDH1A1SMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL29208060 | 0.71 | BRD4 (0.38) | ALDH1A1SMN1; SMN2HTR2ACHEK1CHEK2 | |
| SCHEMBL13543091 | 0.70 | ATM (0.49) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964547-A | Urea compound and application thereof as Sigma2 and 5HT2A dual-target inhibitor | 瀚远医药有限公司 | 2024-05-03 | — | — | CN | disclosed |