Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | ELANE | P08246 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | FABP7 | O15540 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21400167 | 0.89 | HTT (0.51) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL11823665 | 0.86 | KMT2A (0.83) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL10987727 | 0.85 | HTT (0.47) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL10987720 | 0.85 | HTT (0.47) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL28237429 | 0.84 | KMT2A (0.61) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL10986181 | 0.83 | KMT2A (0.45) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL10986185 | 0.83 | KMT2A (0.45) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL10991574 | 0.82 | HTT (0.44) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL10991570 | 0.82 | HTT (0.44) | KMT2AHTTSMN1; SMN2TDP1ELANE | |
| SCHEMBL10991899 | 0.81 | HTT (0.43) | KMT2AHTTSMN1; SMN2TDP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813284-A | Halogenated acethydrazide as AEP inhibitor | 豪夫迈·罗氏有限公司 | 2024-04-02 | — | — | CN | disclosed |