Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29208857 | 1.00 | EGFR (0.51) | EGFRLRRK2BTKALKMAP4K1 | |
| SCHEMBL29208813 | 0.92 | EGFR (0.44) | EGFRBTK | |
| SCHEMBL29208834 | 0.92 | EGFR (0.48) | EGFRBTK | |
| SCHEMBL29208809 | 0.91 | EGFR (0.53) | EGFR | |
| SCHEMBL29208826 | 0.91 | EGFR (0.53) | EGFRLRRK2BTKALKMAP4K1 | |
| SCHEMBL25297038 | 0.90 | EGFR (0.48) | EGFRBTK | |
| SCHEMBL29208751 | 0.90 | EGFR (0.45) | EGFRBTK | |
| SCHEMBL25300965 | 0.89 | EGFR (0.43) | EGFRBTKALKMAP4K1 | |
| SCHEMBL29208855 | 0.86 | EGFR (0.51) | EGFR | |
| SCHEMBL29208808 | 0.85 | EGFR (0.52) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538072-B | Aminopyrimidine EGFR inhibitors | 齐鲁制药有限公司 | 2024-02-06 | — | — | CN | disclosed |